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KMID : 1144320120440010001
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감염과 화학요법
2012 Volume.44 No. 1 p.1 ~ p.4
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Clinical and Laboratory Characteristics of Pandemic Influenza A/H1N1 2009 Infection among Patients with Malignancy in Korea
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Goong Hyeon-Jeong
Seo Yu-Ri
Yoon La-Young
Kwon Soon-Ha
Lee Eun-Jung
Jeon Min-Hyok
Kim Tae-Hyong
Hong Dae-Sik
Choo Eun-Ju
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Abstract
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Background: Patients with malignancy are considered to be at high risk of severe pandemic influenza A/H1N1 2009. This study was conducted to identify the severity of pandemic influenza A/H1N1 2009 among patients with malignancy.
Materials and Methods: Between August 2009 and December 2009, we reviewed clinical data and medical records of 31 patients with malignancy and 63 hospitalized patients without malignancy.
Results: Eighty-three patients with laboratory-confirmed pandemic influenza A/H1N1 2009 were admitted. The rate of ICU admission was higher among patients with malignancy (without malignancy 13% vs with malignancy 35%, P=0.024). The mortality rate was higher among patients with malignancy (without malignancy 6% vs with malignancy 25%, P=0.033). Patients using immunosuppressants showed a higher rate of lower respiratory tract infection (83% vs 24%, P=0.013).
Conclusions: Pandemic influenza A/H1N1 2009 in patients with malignancy was more severe than in patients without malignancy.
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KEYWORD
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Pandemic influenza A/H1N1 2009, Malignancy
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